Girls Next Door: The Bunny House is the newest spin-off of The Girls Next Door. After the Shannon Twins moved into the Playmate house, and then out on their own, Crystal Harris was left as the one and only girlfriend of Hugh Hefner. Girls Next Door: The Bunny House depicts the lives of Crystal and all the girls that live in the house across from the Playboy Mansion.

The girls starring in The Bunny House include Playmates Crystal Harris (December 2009), Crystal McCahill (May 2009), Jayde Nicole (January 2007), Kimberly Phillips (September 2009), Jennifer Pershing (March 2009), Jaime Edmondson (January 2010), Hope Dworaczyk (April 2009), Kayla Collins (August 2008), Claire Sinclair (October 2010); Anna Berglund (January 2011) and Cyber Girl, Cristal Camden.

A special backdoor pilot episode of The Bunny House aired on August 8, 2010 on E! which depicted Claire adjusting to her new life as a Playmate and Hope preparing for her 2010 Playmate of the Year awards ceremony.

The show unfortunately did not get picked up for a full season.